Tuesday, February 7, 2023

Preparation of Liposomes

 Liposomes Introduction and Preparation by Zoraiz Haider


Lipids for Liposomes: Selection, Preparation and Application

Di Bush, Avanti Polar Lipids

Microfluidic Production of Liposomes

Yvonne Perrie, Strathclyde University
  • Microfluidic production of liposome
  • Visual appearance of liposome under microscope, particile size distribution, 
  • Phase transition temperature


Plasma membrane | Transition temperature

By Shantanu Kolhe
  • Behavior of lipids in the fluidity of plasma membrane.

Cell membrane fluidity and role of cholesterol in membrane fluidity

By Shomu's Biology
  • Cholesterol has a big bulky hydrophobic body and a very small hydrophilic group (-OH),
  • In this video the role of Cholesterol in maintaining the membrane fluidity is discussed.
  • At higher temperature, cholesterol decreases membrane-fluidity. Cholesterol provides large surface area for hydrophobic interaction with the long tails of the surrounding lipid chains of the phospholipids. Thus makes the lipid membrane more rigid.
  • At lower temperature, cholesterol molecules push the closely packed long tails of the phospholipids. Thus cholesterol increases the membrane-fluidity.
  • Therefore, Cholesterol molecules provide the optimum fluidity of the lipid bilayers at both higher and lower temperatures.




Lab 5 Synthesis and Characterization of Liposomes


Making Liposomes


HOW TO MAKE LIPID NANOPARTICLES - A day in the life of a PhD


LINK

Making Liposomal Vitamin C: a tutorial
by 
Henrik Eiriksson